Microwave-Based Microfluidic Sensor for Non-Destructive and Quantitative Glucose Monitoring in Aqueous Solution

This paper presents a reliable microwave and microfluidic miniature sensor dedicated to the measurement of glucose concentration in aqueous solution. The device; which is integrated with microtechnologies; is made of a bandstop filter implemented in a thin film microstrip technology combined with a fluidic microchannel. Glucose aqueous solutions have been characterized for concentration ranging from 80 g/L down to 0.3 g/L and are identified with the normalized insertion loss at optimal frequency. The sensitivity of the sensor has consequently been estimated at 7.6 × 10-3 dB/(g/L); together with the experimental uncertainty; the resolution of the sensor comes to 0.4 g/L. These results demonstrate the potentialities of such a sensor for the quantitative analysis of glucose in aqueous solution.